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Archive for the ‘Novartis’ Category

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TODAY’S NEWS:

Prostate cancer drug treatment (Sanofi) approved on the fast track. But – a warning flag for S-A about possible Lantus/cancer link.

Bayer and OncoMed to co-develop oncology drugs in new agreement.

Novartis‘ blood cancer drug Tasigna gets approval for earlier use with CML.

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SocialRx – pharma social media resources. A page full of goodies, newly updated from us here at Impactiviti. Enjoy!

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Sex pills for women. Count me among the skeptics. And, medical flops of the decade (from Forbes).

JUST FOR FUN

Just where in the world is that South Africa place??

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Had a great time last week at the SPBT conference. Planning to get out a summary post later this week…

TODAY’S NEWS:

Big news for Novartis: FDA panel unanimously recommends approval for oral MS drug – A Food and Drug Administration panel has unanimously backed the safety and effectiveness of Novartis’  multiple sclerosis treatment fingolimod. The panel voted 25-0 in support of fingolimod’s “substantial evidence of effectiveness” in treating patients with relapsing remitting multiple sclerosis. That makes it likely the drug will be the first oral MS treatment to gain FDA approval, beating Merck, Sanofi  and Teva – all of which are developing their own oral MS drugs – to the punchmore

Glaxo cuts 700 more sales/marketing positions – A Glaxo spokeswoman said 700 sales and marketing staffers (and related support staff) have taken buyout offers in recent months, while others’ jobs are being cut. She declined to give a total figure, but said the cuts are affecting “a variety of different positions in the U.S. pharma commercial staff.”more

Uncomfortable links being investigated – ARB high blood pressure drugs/cancer; Daiichi‘s Benicar and heart disease; troubling new data on GSK‘s Avandia and heart disease.

A “pill mill” in Kansas and multiple fatalities from the “lollipop of death.”

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Coaching skills. Our Impactiviti partner network has the experienced and recommended vendors to help you bring your coaching program to the next level.  Contact us (stevew at impactiviti dot com, or phone at 973-947-7429) for recommendations.

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Fresh from the tube this weekend: the first ever DTC commercial for medical devices?

JUST FOR FUN

This may just be the most hideous website “designed” by man. Do not click with any consumables in your mouth…

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Impactiviti Daily will not be published next week, as I will be attending the annual Society of Pharmaceutical and Biotech Trainers conference (SPBT) in Orlando.

TODAY’S NEWS:

As the pre-ASCO news heats up, the big headline will be leukemia treatments – specifically, BMS‘ Sprycel and Novartis‘ Gleevec and Tasigna (just inTasigna shown superior to Gleevec in slowing CML: 18-month results). Treatments in this class, by the way, are something near miracle drugs. They’ve totally revolutionized blood cancer treatments. In related news, Novartis’ Afinitor (approved for kidney cancer) meets goals in a trial for pancreatic cancer.

Why should you be interested in a “nanosponge”? Well, there’s this – Scientists have found that a delivery system based on a technique called nanosponge is three to five times more effective at reducing tumor growth than direct injectionmore

Will Amgen‘s new osteoporosis drug Prolia find its true home in oncology treatment? – The company has also applied for FDA approval to market the drug to breast cancer and prostate cancer patients who are undergoing a hormone treatment that weakens their bones. What’s more, the company is conducting tests designed to show that Prolia prevents cancer from spreading to the bones — an indication that could push sales of the drug to as much as $6 billion annually, some analysts predictmore Also – huge sales force push for Prolia.

20% of high school students abuse prescription drugs. Wow – sobering.

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Simulations/Gaming. Live training simulations, digital sims (eLearning) and on-line games – our partner network has the expertise you need.  Contact us (stevew at impactiviti dot com, or phone at 973-947-7429) for recommendations.

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How to reduce e-mail ping-pong. You know all that back-and-forth? Here’s a way to undercut it at the start!

JUST FOR FUN

See-through animals. Ten of them. Amazing.

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Novartis’ CibaVision subsidiary has released a new iPhone app, called the Academy for Eyecare Excellence. I have downloaded it and am going to write this review “live” – that is, give my impressions as I walk through it. I believe that intuitive user interface is the key to good software design, so let’s see how this app strikes a newbie from a user experience point of view.

First up is a required registration page, asking for first name, last name, email, zip code, country, and profession. Below that there are a couple of notification options (for updates), and a link to the Privacy Policy.

Right off, I’d prefer to have a brief explanation why this amount of info is being requested. It’s intrusive compared to most iPhone apps, and may be a barrier to entry. Now, there may very well be excellent reasons to ask for it – but if so, please share them up front in capsule form (you do get a better idea by reading the detailed Privacy Policy).

When I first use any app, I want to feel a sense of intuitive ease with the interface, AND I’d like a little “Wow” factor. The home page interface is a bit busy, but the Intro video of two guys talking about what the app can do for you is very impressive – smooth, hi-res, and motivating. Thumbs up on that idea!

From the initial screen, the user can jump to Courses, Video, and Articles. Let’s try Courses…OK, two courses present (on contact lenses, of course), several future courses listed. The course is structured in topical nuggets, each of which is a tasty combination of video and animation with nice, clear narration. I cannot comment on how helpful these little courses will be for eyecare professionals, but I can say, as someone with a lot of background in eLearning design, that this is pretty good stuff from a production standpoint. Thumbs up here.

The Video section is just promo videos for the digital Ciba educational properties, including this app. This could eventually be a potential repository for helpful little practical hints, or clinical updates, if Ciba heads in that direction – right now, it seems like a placeholder. Thumb at rest in horizontal position.

Articles doesn’t go anywhere. I assume there will be resources populating this at some point. Thumb hiding.

On the bottom navigation bar is a button for Academy, which opens up (essentially) a miniaturized website explaining CibaVision’s educational approach and offerings. The iPhone form factor is not ideal for information structured this way – small type and standard web navigation design. Thumbs down – not on the idea of explaining more about the offerings, but on the information design. There is also a button fro Prof. Affairs which currently goes nowhere.

-> It occurs to me that perhaps the two non-functional buttons are because I registered as an “Other”, not as one of the designated titles for an eyecare professional. So, I just left the app and registered under a different name, as an Opthamologist. And, sure enough, now those nav buttons are occupied! The Prof. Affairs is just a repeat of the intro video – a placeholder, nothing to see here – but the Articles now show a couple of article summaries with a link to the .pdf. Sparse here at launch, but the potential is there. Plus, you are invited to pop open (to full screen) an ad for one of the CibaVision contact lens products.

There is also a Back and a More button on the bottom – Back does what you’d expect, and More gives links to CibaVision site; Acknowledgements; a Contact link (which opens up your e-mail); and Tell a Friend (also e-mail driven). Nothing special.

OK, let’s sum up:

Putting on my branding hat: The visual design, naming, and branding are mediocre. The graphical elements used, and page layouts, are only so-so.

Putting on my application user experience hat: It has potential. Right now, I question the value, especially for the amount of personal information I’ve “given up” at registration. And the experience is “choppy” and stitched together – cool video here, clunky web interface there, etc. The app doesn’t feel smooth and well-integrated (yet).

Putting on my eLearning/professional education hat: Very nice. With lots of potential to evolve.

It is a one-way application – nothing truly interactive or social about it. I think a lot of first-gen pharma apps will fall into that camp. I’d have to say that this one is not particularly compelling, unless an eyecare professional really needs those courses in the palm of their hands. Then, there’s clear value.

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TODAY’S NEWS:

Watson gets FDA approval to start shipping generic Valtrex.

Novartis oral MS drug – FDA extends review another 3 months – Novartis will have to wait a bit longer in its bid to get the first oral treatment for multiple sclerosis on the market after regulators in the USA put back a review of Gilenia. The US Food and Drug Administration has extended by three months, to September, its review period for Gilenia (fingolimod), previously known as FTY720more

Genzyme: Big fine, big changes to get manufacturing back under control.

Another day, another whistleblower suit comes to light. This time, Wyeth and Rapamune promotion for unapproved uses.

Layoffs at Quintiles.

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The Three “I’s” of Tomorrow’s Successful Company. An important perspective from Dennis Urbaniak (VP U.S. Diabetes, Sanofi-Aventis). Titles, Budgets, and Staff are out – Ideas, Initiative, and Inspiration are in.

JUST FOR FUN

50 Beautiful Examples of Architecture Photography.———-

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TODAY’S NEWS

Novartis: huge punitive fine in discrimination case. $250 million game-changing dollars.

FDA to the public – let’s talk more. Or, tell us more about what we should tell you.

GSK and more Avandia flak. This story will never end, it seems.

Pfizer and multiple corporate cultures. An interesting interview at Forbes magazine.

The Manual of Clinical Psychopharmacology gives a raspberry to the Vanda/Novartis schizophrenia drug Fanapt.

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Software training. The Impactiviti partner network has the providers you need for training on software systems. Contact us (stevew at impactiviti dot com, or phone at 973-947-7429) for recommendations.

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Good advice for all situations, including business: Give them your heart, then your head. From my friend Drew McLellan.

JUST FOR FUN

Visual treat. The stunning colors of Glacier National Park. I visited there once, years ago – it really is magnificent! And – Slow Motion Gum And Gelatin. Cooler than you might think (quick video).

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TODAY’S NEWS

Novartis loses this round on the big discrimination suit – A federal jury in New York reached a verdict on Monday requiring Novartis Pharmaceuticals to pay $3.36 million to 12 former female sales representatives for discrimination in pay and promotionsmore

With a sweetened bid, Astellas lands OSI Pharmaceuticals.

Novo Nordisk doing well! And continuing high market expectations for Celgene.

Glaxo‘s big bet on a new type of cardiovascular treatment.

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“Basic” Rep New Hire Training. The Impactiviti partner network has the providers you need for new hire training – from selling skills to therapeutic/product training to compliance to much more! Contact us (stevew at impactiviti dot com, or phone at 973-947-7429) for recommendations.

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The Ultimate List: 300 up-to-date Social Media Statistics

JUST FOR FUN

The World’s Most Bizarre Man-Made Disasters. Maybe this isn’t “Just For Fun,” but it’s still fascinating…

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TODAY’S NEWS

A rough patch for J&Joff-label Topomax promotion; Corporate Integrity Agreement (CIA) means “ride-alongs”; OTC product recalls. Ouch.

Glaxo and Novartis dinged by FDA for potentially misleading promotions. More here on the Novartis situation, which involves Gleevec websites.

Intermune gets major setback for lung treatment – InterMune took its best case for pirfenidone to the FDA, and lost. The agency ruled Tuesday afternoon that the developer would need to mount a new clinical trial for the drug before it could provide a green light for marketingmore

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Outsourced Training – Sometimes, you don’t have the staffing to meet all the training needs (short-term or long-term). We can help.  Contact us (stevew at impactiviti dot com, or phone at 973-947-7429) for recommendations.

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Moving Beyond Blue – my review of a book by an individual struggling with depression, OCD, anxiety, and more.

JUST FOR FUN

Gorgeous pictures of railway bridges. Lots of ’em!

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COMING UP SOON: BDI’s Social Communications and Healthcare half-day gathering. NYC, May 11 – all details here. I will be leading a roundtable. Use discount code IMPACT for $155 registration rate.

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TODAY’S NEWS

Allergan – Rolling high-stakes legal dice re: Botox. Here and here.

Novo’s Victoza: nice results in comparison with Merck‘s Januvia. Plus, an experimental Januvia competitor gets dropped by Forest Labs.

Experimental once-a-day malaria drug looking really good – An experimental once-a-day malaria drug worked as well at treating the mosquito-borne illness as Novartis AG’s twice-daily pill Coartem, according to a study published today in the journal Lancetmore

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Account Management Training – Need to make your account managers more effective? Creative and successful programs are available from Impactiviti’s partner network.  Contact us (stevew at impactiviti dot com, or phone at 973-947-7429) for recommendations.

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Surround Yourself with Smart People.

JUST FOR FUN

Serene Sunrises. 40. A visual treat.

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TODAY’S NEWS

Novartis gets niche transplant drug approved in US –  Drug developer Novartis AG said Thursday it received Food and Drug Administration for the organ-rejection drug Zortress. The drug was first approved outside the U.S. six years ago as Certican and is available in more than 70 countries. It is used to prevent organ rejection in kidney transplant patients. The company reported $118 million in sales in 2009more. Meanwhile, ex-Novartis executive moves on to head up Bayer HealthCare.

Merck growing its vaccines business with an acquisition.

Patient adherence: an immensely costly problem – Medical costs of patient non-adherence to therapy costs the US $106 billion each year, according to an Express Scripts study, and missed opportunities for use of cheaper meds and delivery systems costs another $57 billionmore

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eLearning Simulations – One of the best ways to learn, when things cannot be done live/on-site, is with well-crafted simulations. The Impactiviti Partner Network is your resource if you’re looking for great partners in technology and instructional design.  Contact us (stevew at impactiviti dot com, or phone at 973-947-7429) for recommendations.

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The Intersection of Life, Business, and Social Media. According to me. In 2 graphics.

JUST FOR FUN

Ten lovely bridge designs.

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