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Archive for the ‘Biotech’ Category

There’s a ton of stuff going on this week, plus we’re in pre-ASCO mode (so lots of oncology news - scroll down for those headlines). Here we go:
What’s a vaptan? Maybe something pretty exciting - A new class of drugs called vaptans may be able to treat a wide variety of conditions including painful periods, [...]

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Merck the latest to make major cuts to its sales force - The unwinding of the Big Pharma sales armies continues apace, with Merck saying late today that it’s cutting its U.S. sales force by 1,200 positions, or about 14% from 8,500 reps at the start of 2007…more (and, in a strange twist, it appears [...]

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BMS to sell off ConvaTec - Drug developer Bristol-Myers Squibb Co. said Friday it will sell its would therapy and surgical care unit for $4.1 billion to two private equity firms…more
Big cutback/merger action at J&J - sales and marketing for Ortho Biotech and Centocor to join, 400 jobs to go - Johnson & Johnson yesterday [...]

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Statin and Alzheimer’s…ummm, maybe not - More news from that big neurology meeting : Lipitor doesn’t help slow cognitive decline in Alzheimer’s patients, researchers said this week. That’s something of a disappointment, given that it was a big, randomized study, and earlier data had showed promise. On the other hand, Alzheimer’s patients who took [...]

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Breaking news from the ACC:
Vytorin/Zetia gets panned - shows no benefit on the primary endpoint, though effective in reducing some markers. Doctors now wary and skeptical. Merck and Schering-Plough comment. Good summary with more links from Ed Silverman (Pharmlot blog - one of the best btw!) here.
Prasugrel gets a boost - The investigational antiplatelet [...]

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Some interesting oncology results:
Millennium’s Velcade used in combo therapy for multiple myeloma shows impressive results.
Cephalon’s Treanda shows impressive remission numbers for CLL, and effectiveness in non-Hodgins lymphoma (NHL).
Celgene’s Revlimid continues to produce good results at a low-dose regimen.
Novartis‘ Gleevec: effective at halting leukemia progression up to 6 years.
Eisai decides to grab MGI Pharma, and its [...]

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Glaxo buying Reliant - GlaxoSmithKline Plc has agreed to buy privately held heart drug specialist Reliant Pharmaceuticals for $1.65 billion in cash, in a move to boost its flagging drug sales in the United States…more
J&J says good-bye to $440 mil - Johnson & Johnson said on Thursday its fourth-quarter results would include a special after-tax, [...]

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Looks, on the surface, like a good match of products and market presence - Celgene buys Pharmion. And, in other important oncology news, Nexavar (from Bayer) gets expedited approval for liver cancer.

Also, Schering cleared to take over Organon - by divesting bird vaccines to Wyeth.

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The Good Stuff:
BMS gets approval for new oncology drug (for breast cancer) Ixempra.
Merck gets new HIV drug (Isentress) approved in the U.S. And, their Januvia diabetes drug gets new uses approved.
Abraxis gets cancer drugs approved.
J&J gets Doribax (for intra-abdominal and urinary tract infections) approved.
Bayer reports upbeat MS drug results.
Glaxo: new use of HIV drug Lexiva [...]

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Novartis gets approval for Reclast, a once-per-year osteoporosis treatment. That’s a game-changer - very cool advance that should lead to far better patient compliance.
A long-ish article on Wyeth’s efforts to find Alzheimer’s treatments. It’s a risky R&D commitment, but nobody questions that desirability of finding new advances here. Also, MedAd News has a brief interview [...]

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